Module description

Medical Engineering (MTM)

Biosignal Analysis and Electrophysiology

Recommended prior knowledge

Admission to the master degree course in medical technology at the Hochschule Offenburg and the knowledge acquired in the Bachelor's degree program medical technology of the Hochschule Offenburg biosignal processing and hemodynamic management

Teaching Methods Lecture/Seminar/Lab
Learning objectives / competencies

After successfully completing of this module, students capable of conventional and high resolution electrical and impedance cardiographic biosignals with and without signal averaging technique measured in the time and frequency domains, conventional 12-channel electrocardiograms in the x, y, z range to transform and vector field and measure micro potentials in ischemic and non-ischemic cardiomyopathy and cardiac pacemakers and defibrillators, To analyze biosignals by means of spectro-temporal mapping with and without electrical stimulation, electrical and impedance cardiographic biosignals with different sampling frequencies to merge, bradycardia and tachycardia arrhythmia to initiate and terminate. to evaluate electrical cardiac desynchronization, fractional atrial and ventricular biosignals to analyze and optimize cardiac resynchronization therapy and contractility modulation.

Duration 2
SWS 4.0
Effort
Classes 60h
Self-study / group work: 180h
Workload 240h
ECTS 8.0
Requirements for awarding credit points

Presentation (RE), K90 exam (K90) and laboratory work (LA)

Credits and Grades

8 ECTS

Responsible Person

Prof. Dr.-Ing. med. habil. Matthias Heinke

Recommended Semester 1-2
Frequency Annually (ss)
Usability

Master medical technology

Lectures

Labor Biosignalanalyse und Elektrophysiologie

Type Labor
Nr. EMI2515
SWS 2.0
Lecture Content

The master laboratory bio-signal analysis and Electrophysiology allows an efficient and practical training in the fields of conventional and high resolution bio-signal analysis and Electrophysiology in the time, spectral, and vector field of clinically relevant biosignals with modern biosignal analysis systems and intracardiac electrophysiology system: Sinus rhythm biosignal analysis with and without ventricular and supraventricular extrasystoles, left cardiac focus ECG Osypka TO4 single-chamber electrodes atrial and ventricular desynchronization biosignal analysis, congestive heart failure, Boston Scientific Cognis 100 D CRT-D with SmartDelay function Left bundle branch block and right bundle branch block bio signal analysis, reduced pumping function, dilated cardiomyopathy, Boston Scientific Punctua VVI ICD and Vitality2 VR ICD Atrial flutter biosignal analysis, atrial overdrive stimulation of atrial flutter, Osypka TO8 dual-Chamber electrodes, focused stimulation in atrial flutter, atrial fibrillation biosignal analysis, coronary heart disease, Boston Scientific Livian H240 CRT-D, Biosignal analysis after cryo-ablation of atrial fibrillation signal averaging biosignal analysis, electromechanical biosignal fusion of Bard lab duo electrical bio signals with 1000 Hz sampling frequency and medis cardio vascular lab impedance cardiographic biosignals with 200 Hz sampling frequency, with and without the CRT-D system, dilated cardiomyopathy, coronary artery disease, reference group spectro temporal mapping, conventional 12 channel ECG, X, Y, Z, vector ECG, left heart ECG, cardiac micro potential, fractional biosignals, ischemic and non-ischemic cardiomyopathy, reference group, QRS triggered signal averaging, vector electrocardiography, Boston Scientific Livian H240 CRT-D, Livian H247 CRT-D, renewal TR2 CRT-P, vitality VVI-ICD, Medtronic Maximo II CRT-D, marquise VR7230 ICD 3D vector ECG loop, conventional 12 channel ECG, X, Y, Z, ECG, left heart ECG, cardiac excitation spread with and without congestive heart failure and stimulation. Medtronic InSyc Maximo CRT-D, Boston Scientific Livian H247, Livian H240 CRT-D intracardiac electrocardiography with programmed atrial and ventricular stimulation to the initiation, termination and catheter-based ablation tachycardia heart rhythm disorders with the EP-tracer system additional and individually tailored assignments to the master laboratory biosignal analysis and electrophysiology

Literature

Medical and Biological Engineering and Computing, Journal of the International Federation for Medical and Biological Engineering, Springer
EP Europace, Journal of the European Heart Rhythm Association, Oxford University Press
Biomedical Engineering, Biomedizinische Technik, De Gruyter
Clinical Research in Cardiology, International Journal for clinical cardiovascular research, Springer
Karrenberg, Signale - Prozesse - Systeme, Sechste Auflage, Springer


Eisenträger, D., Heinke, M., Ismer, B., Voss, A., Surber, R., Kühnert, H., Prochnau, D., Solbrig, O., Querengässer, J., Figulla, H.R., Electromechanical Interventricular Delay with Transesophageal Left Ventricular ECG and Impedance Cardiography Recording in Patients With and Without Heart Failure, World Congress on Medical Physics and Biomedical Engineering, September 7-12, 2009, Munich, Germany, IFMBE Proceedings 25, Abstract 115, 2009


Haltenberger, A., Heinke, M., Ismer, B., Kuehnert, H., Kuethe, F., Eisentraeger, D., Surber, R., Prochnau, D., Lorenz, M., Figulla, H. R., Transesophageal left cardiac electrocardiography for evaluation of interventricular and interatrial conduction delay before and after premature ventricular contraction in heart faiilure patients, Biomed Tech; 56 (Suppl. 1), 547, 2011

Boston Scientific, Systemhandbuch Livian Cardiale Resynchronisationtherapie mit Defibrillationsfunktion (CRT-D), 370 Seiten, 2007

Seminar Biosignalanalyse und Elektrophysiologie

Type Vorlesung/Seminar
Nr. EMI2514
SWS 2.0
Lecture Content

Presentations on cardiology publications and transesophageal electrophysiology studies transesophageal intra cardiac and implant-based stimulation, derivation and evaluation, initiation and termination of arrhythmia biosignal and function analysis of stimulus formation and conduction supraventricular tachycardia, SVT and SVES atrial tachycardia AT AV node re-enty tachycardia AVNRT AV re-entry tachycardia AVRT atrial flutter AFL atrial fibrillation AF ventricular tachycardia VT, VES, and HRT practical biosignal analysis and electrophysiology of ventricular flutter VFL (pulseless VT), ventricular fibrillation of VF Torsades de pointes tachycardia TdP Brugada syndrome (ECG: RSB and ST Elevation) long-QT syndrome and short QT syndrome

Literature

Medical and Biological Engineering and Computing, Journal of the International Federation for Medical and Biological Engineering, Springer
EP Europace, Journal of the European Heart Rhythm Association, Oxford University Press
Biomedical Engineering / Biomedizinische Technik, De Gruyter
Clinical Research in Cardiology, International Journal for clinical cardiovascular research, Springer
Signale - Prozesse - Systeme, Karrenberg, Sechste Auflage, Springer
Prochnau, D., Forberg, T., Kühnert, H., Heinke, M., Figulla, H.R., Surber, R., Optimization of the atrio-ventricular delay during cardiac resynchronization therapy using a device for non-invasive meas-urement of cardiac index at rest and during exercise, Europace 14 2012, 249-253
Heinke, M., Ismer, B., Kühnert, H., Figulla, H.R., Transesophageal left ventricular electrogram-recording and temporary pacing to improve patient selection for cardiac resynchronization. Med Biol Eng Comput, 2011, 49: 851-858
Kuehnert, H., Figulla, H.R., Ismer, B., Heinke, M., New frontiers of supraventricular tachycardia and atrial flutter evaluation and catheter ablation. Biomed Tech 2012; 57, 371-373, Walter de Gruyter, Berlin, Boston, DOI 10.1515/bmt‐2012‐4169