Module description

Medical Engineering (MTM)

Applied Neurosciences

Recommended prior knowledge

Knowledge of neuroanatomy and neurophysiology, knowledge of neuroradiology and neuro-nuclear medicine, knowledge of clinical neurology and clinical psychiatry

Teaching Methods Lecture/Seminar/Lab
Learning objectives / competencies

After successful completion of this course, students should be able:
To know important subject areas, knowledge and research areas of the neurosciences (neurology, psychiatry, neurobiology) and to reliably transfer these to existing and future medical applications; to independently prepare specific neuropsychiatric disorders in presentations in detail and intensively and discuss them in the group; to show the possibilities and limitations of medical technology in neurosciences; to deepen and understand the essential contents of applied neurosciences by means of specially conducted laboratory experiments and to find out and understand relationships and links.

The competences associated with the attendance of this module include subject expertise and subject-related methodological and social competences.


Duration 2
SWS 4.0
Classes 60h
Self-study / group work: 180h
Workload 240h
ECTS 8.0
Requirements for awarding credit points

Presentation, written examination (K90), laboratory work

Credits and Grades


Responsible Person

Prof. Dr. med. Andreas Otte

Recommended Semester 1-2
Frequency Annually (ss)

Master of Science in Medical Engineering


Seminar Angewandte Neurowissenschaften

Type Vorlesung/Seminar
Nr. EMI2512
SWS 2.0
Lecture Content

The course is subdivided into two parts. Part I has lecture characteristics and part II seminar character.

Part I covers the following topics:
Introduction; topics in neurosciences; application of medical knowledge; developments and research fields in neurosciences; neurophysiological processes (aging, thinking, neurofeedback, ePriming, cerebral plasticity)

In Part II, special neuroscientific diseases under medical aspects are prepared in detail by the students, presented before the group and discussed intensively. The presentation is divided into the following:
History, epidemiology, clinic, diagnostics, therapy, medical technology (what can it measure, what imaging is reasonable, what technical therapeutic approaches are possible, what could be explored in the field of medical technology for this disease?)



Hacke, W., Neurologie, Springer, Berlin, Heidelberg; in the current edition and the respective current edition year

Huber, G., Psychiatrie: Lehrbuch für Studium und Weiterbildung, Schattauer, Stuttgart, in the current edition and the respective current edition year

Rohen, J.W., Funktionelle Neuroanatomie - Lehrbuch und Atlas, Schattauer, Stuttgart; in the current edition and the respective current edition year

Rüegg, J.C., Gehirn, Psyche und Körper. Neurobiologie von Psychosomatik und Psychotherapie, Schattauer, Stuttgart; in the current edition and the respective current edition year

Schiepek, G., Neurobiologie der Psychotherapie, Schattauer, Stuttgart; in the current edition and the respective current edition year

Otte, A., Dierckx, RAJO, de Vries EFJ, van Waarde A., Luiten PGM, PET and SPECT of Neurobiological Systems, Springer Heidelberg, New York, Dordrecht, London, 2014

Otte, A., Dierckx, RAJO, De Vries EFJ, Van Waarde A., Den Boer JA, PET and SPECT in Psychiatry, Springer Heidelberg, New York, Dordrecht, London, 2014

Dierckx, RAJO, Otte, A., De Vries, EFJ, Van Waarde, A., Leenders KL, PET and SPECT in Neurology, Springer Heidelberg, New York, Dordrecht, London, 2014

Schulze, H., Streifzüge durch unser Gehirn, Umschau Zeitschriftenverlag, Sulzbach im Taunus, 2011

Bonhoeffer, T., Gruss, P., Zukunft Gehirn: Neue Erkenntnisse, neue Herausforderungen, Ein Report der Max-Planck-Gesellschaft, Verlag C.H. Beck, München, 2011

Clegg, B., Die Vermessung des Körpers: Warum unsere Haut sehen und die Nase durch die Zeit reisen kann, Hanser Verlag, München, 2013

Velliste, M., Perel, S., Spalding, MC, Whitford, AS, Schwartz AB, Cortical control of a prosthetic arm for self-feeding, Nature, 2008

Otte, A., Neculae A, Curticapean, D., Near-infrared spectroscopy for real-time brain perfusion diagnostics in patients with late whiplash syndrome, in: Frontiers in Optics 2013, P. Delyett, Jr. and D. Gauthier, eds., OSA Technical Digest (online) (Optical Society of America, 2013), paper JW3A.25. Link:

Okun, MS., Deep-Brain Stimulation for Parkinson's, Disease, N Engl J Med, 2012

Otte, A., Deep-Brain Stimulation for Parkinson's Disease, N Engl J Med, 2013

Labor NeuroScience

Type Labor
Nr. EMI2513
SWS 2.0
Lecture Content

The NeuroScience laboratory deepens the theory of neurosciences through appropriate practical implementation tasks. The students should also learn to implement a demanding task independently and correctly.
The NeuroScience laboratory offers the following modern workplaces, where neuroscientific experiments are carried out in small groups (preferably 2 students per workplace):

Workplace simulations (age simulator, hemiparesis simulator); workplace muscle endurance tests for electromyography (EMG); workplace functional near infrared spectroscopy (fNRIS) (perfusion measurements in the brain using fNIRS); workplace electroencephalography (EEG); workplace neurostimulation (measurement of the nerve conduction velocity with the help of a Biopac neurostimulator); workplace artery stenosis simulation using color doppler sonography


In addition to the literature described in the above Lecture + Seminar Applied Neurosciences the following literature is relevant for the laboratory:

Otte, A., Skriptum zum Labor NeuroScience, Hochschule Offenburg, in the current edition and the respective current edition year

Produkt und Projekt, Wissenschaftliche Grundlagen der Alterssimulation mit GERT, Link: (Zugriff am: 23.04.2014)Filz, S.A., Instant Aging -
Selbsterfahrung des Alterns, Medizinische Inauguraldissertation, Universität Würzburg, 2008

Product manuals from Biopac, Mega Electronics Ltd, Nirxx, Gampt and EDAN